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Oral Colonization by Nosocomial Pathogens During Hospitalization in Invasive Care Unit and Prevention Strategies

Author(s):

Hossein Kazemian, Samane Bourbour, Maryam Beheshti and Abbas Bahador   Pages 1 - 13 ( 13 )

Abstract:


Background: Critically ill patients are very susceptible to a variety of disorders and infections during hospitalization in Intensive Care Units (ICU). Among these problems, nosocomial infections are major causes of morbidity and mortality. Methods: Nosocomial pneumonias, specifically ventilator associated pneumonias have become a major health care issue. The implication of oral care in hospital presents challenges that can prevent or reduce the risk of nosocomial pneumonias in ICU. In this review article, we reviewed the most important nosocomial pathogens which colonize the oral cavity and causes severe infections during hospitalization in ICU. Conclusion: Finally, we discuss about the prevention strategies against oral colonization of nosocomial pathogens includes classic methods and novel methods such as Photodynamic therapy, NO based therapy, anti-virulence therapy and other new under investigation antimicrobial strategies.

Keywords:

Critically ill patients, nosocomial infection, ICU, oral colonization

Affiliation:

Clinical Microbiology Research center, Ilam University of Medical Sciences, Ilam, Clinical Microbiology Research center, Ilam University of Medical Sciences, Ilam



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